Could frog slime cure the flu?

23 April, 2017, 01:44 | Author: Lorena Waters
  • South Indian frog Hydrophylax bahuvistara.    
   Image by Sanil George and Jessica Shartouny

It sounds like weird science, but the slime that coats the skin of South Indian frogs might fight some strains of the flu.

The researchers will look more on how effective this new finding will be to other animals and eventually to humans.

Joint research by scientists from Rajiv Gandhi Centre for Biotechnology (RGCB) here and the US-based Emory Vaccine Center have identified a crucial component from skin mucus of a species of a frog, a peptide that kills all H1influenza viruses.

Frogs naturally secrete slime to help protect them from bacteria and fungi.

The flu-fighting compounds are called peptides, which are short chains of amino acids; those are the building blocks of proteins.

More research is needed to determine if urumin could become a preventive treatment against the flu in humans, and to see if other frog-derived peptides could protect against viruses like dengue and Zika.

H1 flu viruses are targetted by the urumin peptide in the mucus of the frogs.

Justice Department calls New York City 'soft on crime'
It said in a news release that New York City's gang murders are "the predictable effect of the city's "soft on crime" stance". De Leon has been an outspoken critic of the administration's immigration crackdown.

When delivered through the nasal cavities, the compound known as urumin protected unvaccinated mice from a lethal dose of the flu virus. Tests on mice showed that the compound was effective against dozens of H1 strains, including the 2009 pandemic strain, but not against H3N2 and other flu strains.

The researchers found four peptides, or small molecules, within the mucus that were able to kill off flu viruses in the lab.

"It's a natural innate immune mediator that all living organisms maintain", said Josh Jacob, who co-authored the study at Emory University, Georgia.

The substance is a peptide known as "urumin", named after urumi, a flexible sword that originated from the same province where the frog is known to live. The team named the newly discovered peptide "urumin". According to NBC News, the researchers are planning to formulate antiviral drugs out of it to treat people infected by a flu virus. Putting the H in H1, this protein is a key part of how the flu virus grips and attacks healthy human cells.

It is indicated that the peptide from the frog slime will directly kill influenza viruses. Colds also do not result in serious health problems, such as pneumonia, bacterial infections, or hospitalization, while the flu virus can. As opposed to common antiviral peptides that work by punching a hole in the cell membranes, urumin appears to bind the stalk of hemagglutinin.

The study said: "Urumin is a unique class of anti-influenza viricide specifically targeting haemagglutinin". That means scientists need to create a more stable version before the drug can be widely produced or used in human trials.

Tackling the flu isn't just a matter of feeling better in the winter or staying healthy to avoid using up those vacation days.


  • Apple Makes iMovie, iWork Apps Free For iOS And Mac Users

    Apple Makes iMovie, iWork Apps Free For iOS And Mac Users

    Now they too can use iWork, iMovie, and GarageBand on their devices without having to pay a lot of money for Apple's software. By making the applications free for everyone, Apple is significantly increasing the reach of the suite of apps.
    Pres. Trump visits Kenosha for order signing

    Pres. Trump visits Kenosha for order signing

    As Trump approaches his 100-day milestone in the White House, he has failed to pass any serious policies through Congress. Lottery funds more than 65,000 H1-B applications each year with another 20,000 handed out to graduate student workers.
    Fast & Furious Spin-off with The Rock & Statham is ON!

    Fast & Furious Spin-off with The Rock & Statham is ON!

    Now playing across the Philippines, Fast & Furious 8 is distributed by United International Pictures through Columbia Pictures. More chapters in the Furious franchise, which began in 2001, are planned for release in 2019 and 2021.
  • Erik Jones Wins Bristol XFINITY Race

    Erik Jones Wins Bristol XFINITY Race

    Now? The team is winless through the first seven races of the season and looking to break the drought at Bristol Motor Speedway . The race is Sunday at 2 p.m. on FOX on the tight half-mile oval where Carl Edwards won from the pole last season.
    Michigan State DE Auston Robertson Charged with Criminal Sexual Conduct

    Michigan State DE Auston Robertson Charged with Criminal Sexual Conduct

    Three unidentified players have been serving suspensions since February 9 in relation to an alleged sexual assault on January 16. A Michigan State and former Wayne High School football player has been charged with third-degree criminal sexual conduct.
    Microsoft's Wunderlist Replacement, To-Do Is Now Available

    Microsoft's Wunderlist Replacement, To-Do Is Now Available

    The preview is now available for iPhone ( iOS 9.0 or later), Android (4.4 or higher), Windows 10 and Windows 10 Mobile and Web . However, all your tasks are still available in the slide-out sidebar, so you can always get an overview of your schedule.
  • Starbucks barista has meltdown over Unicorn Frappuccino

    Starbucks barista has meltdown over Unicorn Frappuccino

    Now, the obsession has gone even further, thanks to one hairdresser who was inspired by Starbucks' Unicorn Frappuccino . Starbucks said its "baristas will be happy to work with you to find an alternative Frappuccino".
    Britain Could See Its First Full Day without Coal

    Britain Could See Its First Full Day without Coal

    The reason for this is that there is considerable uncertainty over the future role of gas in United Kingdom power generation. Britain's last power station will be forced to close in 2025 , as part of a government plan to phase out the fossil fuel.
    Ronda Rousey announces engagement to fighter Travis Browne

    Ronda Rousey announces engagement to fighter Travis Browne

    She rose to fame and even crossed over to Hollywood, having roles in " The Expendables 3 " and " Furious 7 ". For Ronda , it was a year, so, news about upcoming wedding is really good for UFC champion and her fans.
  • Australia, Japan lobby for TPP-11

    Australia, Japan lobby for TPP-11

    Trump was elected in November, from inviting China to join the pact to doubling down on efforts to forge bilateral trade deals. President Donald Trump, saying a two-way negotiation does not offer the same scope for beneficial trade-offs.
    Patch (hack) unblocks Windows Update in Win7 & 8.1

    Patch (hack) unblocks Windows Update in Win7 & 8.1

    Updated Microsoft's explained how often it intends to offer "feature updates" to Windows 10: twice a year in March and September. That is to say, the use of older Office versions that have dropped into extended support will no longer be possible.
    We are in touch with USA  on H-1B visa programme

    We are in touch with USA on H-1B visa programme

    It said that the country lacks domestic workforce with skill sets needed in IT, healthcare, education and other STEM fields. He explained that now a "visa dependent" company is defined as one that has 15% or more workers on H1-B visas in the US.


Tumult After Judge Orders University To Host White Nationalist Richard Spencer
In a letter from Auburn University provost , the school cited safety concerns for the attempted cancelation. The Auburn Police Division said that those who were arrested were not Auburn students or residents.

Applications for US jobless aid rise but remain at low level
Other data today showed factory activity in the mid-Atlantic region slowed in April amid a pullback in new orders and shipments. The four-week moving average declined to 2.024mn from 2.026mn previously and at the lowest level for close to 17 years.

Dana White Estimates $75M Payday For Conor McGregor in Mayweather Fight
Billed as The Fight of the Century , the fight did an estimated 4.6 million PPV buys. I need to figure out the Mayweather side, and maybe it can't be (figured out).

Air Force intercepts Russian bears in the air
The next day, two Russian bombers were seen only 41 miles from Alaska, though still in global airspace. On Monday , the USA intercepted Russian bombers 100 miles from Kodiak Island, Alaska.

Sonia Gandhi to call May meet to fix Opposition President choice
The JD (U) leader hastened to add that there was no reference to any name in the Nitish-Sonia meeting. The names of both JD (U) veteran Sharad Yadav and NCP chief Sharad Pawar are doing the rounds.